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P3CO guidance issued; funding pause lifted

HHS Framework for Guiding Funding Decisions about Proposed Research Involving Enhanced Potential Pandemic Pathogens replaced the pause. NIH Director Collins announced the lift.

Linked sources

HHS P3CO Framework — Guiding Funding Decisions about Enhanced Potential Pandemic Pathogens
Tier 1 · report · Framework PDF; original phe.gov host defunct, Dec 2017 Wayback snapshot
NIH Lifts Funding Pause on Gain-of-Function Research (Collins statement)
Tier 2 · other · NIH Director statement, Dec 19 2017; live URL since removed, archive copy
Research Involving Enhanced Potential Pandemic Pathogens (NIH media kit)
Tier 2 · other · Live NIH page describing 2014–2017 pause and P3CO oversight

Related contentions

Gain-of-function definitions

Unresolved definitional dispute. Tabak letter (Oct 2021) acknowledged delayed reporting of enhanced growth in mice; NIH still denied ePPP classification.